Cargando…
Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole
Multiple G-quadruplex units in the 3΄-terminal overhang of human telomeric DNA can associate and form multimeric structures. The specific targeting of such distinctive higher-order G-quadruplexes might be a promising strategy for developing selective anticancer agents with fewer side effects. Howeve...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389520/ https://www.ncbi.nlm.nih.gov/pubmed/27923993 http://dx.doi.org/10.1093/nar/gkw1195 |