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Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase

Replication of human immunodeficiency virus 1 (HIV-1) involves conversion of its single-stranded RNA genome to double-stranded DNA, which is integrated into the genome of the host. This conversion is catalyzed by reverse transcriptase (RT), which possesses DNA polymerase and RNase H domains. The ava...

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Detalles Bibliográficos
Autores principales:	Figiel, Małgorzata, Krepl, Miroslav, Poznański, Jarosław, Gołąb, Agnieszka, Šponer, Jiří, Nowotny, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389522/ https://www.ncbi.nlm.nih.gov/pubmed/28108662 http://dx.doi.org/10.1093/nar/gkx004

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