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Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta

Activator protein 1 (AP-1) is a transcription factor that recognizes two versions of a 7-base pair response element, either 5΄-TGAGTCA-3΄ or 5΄-MGAGTCA-3΄ (where M = 5-methylcytosine). These two elements share the feature that 5-methylcytosine and thymine both have a methyl group in the same positio...

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Detalles Bibliográficos
Autores principales: Hong, Samuel, Wang, Dongxue, Horton, John R., Zhang, Xing, Speck, Samuel H., Blumenthal, Robert M., Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389525/
https://www.ncbi.nlm.nih.gov/pubmed/28158710
http://dx.doi.org/10.1093/nar/gkx057