Cargando…

Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript

Muscleblind-like proteins (MBNLs) are regulators of RNA metabolism. During tissue differentiation the level of MBNLs increases, while their functional insufficiency plays a crucial role in myotonic dystrophy (DM). Deep sequencing of RNA molecules cross-linked to immunoprecipitated protein particles...

Descripción completa

Detalles Bibliográficos
Autores principales: Konieczny, Patryk, Stepniak-Konieczna, Ewa, Taylor, Katarzyna, Sznajder, Łukasz J., Sobczak, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389549/
https://www.ncbi.nlm.nih.gov/pubmed/27903900
http://dx.doi.org/10.1093/nar/gkw1158