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Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript
Muscleblind-like proteins (MBNLs) are regulators of RNA metabolism. During tissue differentiation the level of MBNLs increases, while their functional insufficiency plays a crucial role in myotonic dystrophy (DM). Deep sequencing of RNA molecules cross-linked to immunoprecipitated protein particles...
Autores principales: | Konieczny, Patryk, Stepniak-Konieczna, Ewa, Taylor, Katarzyna, Sznajder, Łukasz J., Sobczak, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389549/ https://www.ncbi.nlm.nih.gov/pubmed/27903900 http://dx.doi.org/10.1093/nar/gkw1158 |
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