Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity

Double-stranded DNA minicircles of less than 1000 bp in length have great interest in both fundamental research and therapeutic applications. Although minicircles have shown promising activity in gene therapy thanks to their good biostability and better intracellular trafficking, minicircles down to...

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Detalles Bibliográficos
Autores principales: Thibault, Thomas, Degrouard, Jeril, Baril, Patrick, Pichon, Chantal, Midoux, Patrick, Malinge, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389552/
https://www.ncbi.nlm.nih.gov/pubmed/27899652
http://dx.doi.org/10.1093/nar/gkw1034

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