Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism

Bacteriophages and large dsDNA viruses encode sophisticated machinery to translocate their DNA into a preformed empty capsid. An essential part of this machine, the large terminase protein, processes viral DNA into constituent units utilizing its nuclease activity. Crystal structures of the large te...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Rui-Gang, Jenkins, Huw T., Chechik, Maria, Blagova, Elena V., Lopatina, Anna, Klimuk, Evgeny, Minakhin, Leonid, Severinov, Konstantin, Greive, Sandra J., Antson, Alfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389553/
https://www.ncbi.nlm.nih.gov/pubmed/28100693
http://dx.doi.org/10.1093/nar/gkw1354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389553/
https://www.ncbi.nlm.nih.gov/pubmed/28100693
http://dx.doi.org/10.1093/nar/gkw1354

Ejemplares similares