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Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism

Bacteriophages and large dsDNA viruses encode sophisticated machinery to translocate their DNA into a preformed empty capsid. An essential part of this machine, the large terminase protein, processes viral DNA into constituent units utilizing its nuclease activity. Crystal structures of the large te...

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Detalles Bibliográficos
Autores principales:	Xu, Rui-Gang, Jenkins, Huw T., Chechik, Maria, Blagova, Elena V., Lopatina, Anna, Klimuk, Evgeny, Minakhin, Leonid, Severinov, Konstantin, Greive, Sandra J., Antson, Alfred A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389553/ https://www.ncbi.nlm.nih.gov/pubmed/28100693 http://dx.doi.org/10.1093/nar/gkw1354

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