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Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks

The DNA replication or S-phase checkpoint monitors the integrity of DNA synthesis. Replication stress or DNA damage triggers fork stalling and checkpoint signaling to activate repair pathways. Recovery from checkpoint activation is critical for cell survival following DNA damage. Recovery from the S...

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Detalles Bibliográficos
Autores principales:	Chaudhury, Indrajit, Koepp, Deanna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389566/ https://www.ncbi.nlm.nih.gov/pubmed/27956499 http://dx.doi.org/10.1093/nar/gkw1249

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