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Unusual C΄/D΄ motifs enable box C/D snoRNPs to modify multiple sites in the same rRNA target region

Eukaryotic box C/D small nucleolar (sno)RNPs catalyse the site-specific 2΄-O-methylation of ribosomal RNA. The RNA component (snoRNA) contains guide regions that base-pair with the target site to select the single nucleotide to be modified. The terminal C/D and internal C΄/D΄ motifs in the snoRNA, a...

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Detalles Bibliográficos
Autores principales:	van Nues, Robert Willem, Watkins, Nicholas James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389607/ https://www.ncbi.nlm.nih.gov/pubmed/28204564 http://dx.doi.org/10.1093/nar/gkw842

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