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A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction
The CRISPR (clustered regularly interspaced short palindromic repeats) system protects archaea and bacteria by eliminating nucleic acid invaders in a crRNA-guided manner. The Sulfolobus islandicus type III-B Cmr–α system targets invading nucleic acid at both RNA and DNA levels and DNA targeting reli...
Autores principales: | Han, Wenyuan, Li, Yingjun, Deng, Ling, Feng, Mingxia, Peng, Wenfang, Hallstrøm, Søren, Zhang, Jing, Peng, Nan, Liang, Yun Xiang, White, Malcolm F., She, Qunxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389615/ https://www.ncbi.nlm.nih.gov/pubmed/27986854 http://dx.doi.org/10.1093/nar/gkw1274 |
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