Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5

Autoinhibition enables spatial and temporal regulation of cellular processes by coupling protein activity to surrounding conditions, often via protein partnerships or signaling pathways. We report the molecular basis of DNA-binding autoinhibition of ETS transcription factors ETV1, ETV4 and ETV5, whi...

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Detalles Bibliográficos
Autores principales: Currie, Simon L., Lau, Desmond K. W., Doane, Jedediah J., Whitby, Frank G., Okon, Mark, McIntosh, Lawrence P., Graves, Barbara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389675/
https://www.ncbi.nlm.nih.gov/pubmed/28161714
http://dx.doi.org/10.1093/nar/gkx068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389675/
https://www.ncbi.nlm.nih.gov/pubmed/28161714
http://dx.doi.org/10.1093/nar/gkx068

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