A continuum of mRNP complexes in embryonic microRNA-mediated silencing

MicroRNAs (miRNAs) impinge on the translation and stability of their target mRNAs, and play key roles in development, homeostasis and disease. The gene regulation mechanisms they instigate are largely mediated through the CCR4–NOT deadenylase complex, but the molecular events that occur on target mR...

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Detalles Bibliográficos
Autores principales: Wu, Edlyn, Vashisht, Ajay A., Chapat, Clément, Flamand, Mathieu N., Cohen, Emiliano, Sarov, Mihail, Tabach, Yuval, Sonenberg, Nahum, Wohlschlegel, James, Duchaine, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389717/
https://www.ncbi.nlm.nih.gov/pubmed/28204614
http://dx.doi.org/10.1093/nar/gkw872

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