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RMI1 and TOP3α limit meiotic CO formation through their C-terminal domains
At meiosis, hundreds of programmed DNA double-strand breaks (DSBs) form and are repaired by homologous recombination. From this large number of DSBs, only a subset yields crossovers (COs), with a minimum of one CO per chromosome pair. All DSBs must be repaired and every recombination intermediate mu...
Autores principales: | Séguéla-Arnaud, Mathilde, Choinard, Sandrine, Larchevêque, Cécile, Girard, Chloé, Froger, Nicole, Crismani, Wayne, Mercier, Raphael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389728/ https://www.ncbi.nlm.nih.gov/pubmed/27965412 http://dx.doi.org/10.1093/nar/gkw1210 |
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