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Embryonic loss of human females with partial trisomy 19 identifies region critical for the single active X

To compensate for the sex difference in the number of X chromosomes, human females, like human males have only one active X. The other X chromosomes in cells of both sexes are silenced in utero by XIST, the Inactive X Specific Transcript gene, that is present on all X chromosomes. To investigate the...

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Detalles Bibliográficos
Autores principales: Migeon, Barbara R., Beer, Michael A., Bjornsson, Hans T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389809/
https://www.ncbi.nlm.nih.gov/pubmed/28403217
http://dx.doi.org/10.1371/journal.pone.0170403

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