High GC content causes orphan proteins to be intrinsically disordered

De novo creation of protein coding genes involves the formation of short ORFs from noncoding regions; some of these ORFs might then become fixed in the population. These orphan proteins need to, at the bare minimum, not cause serious harm to the organism, meaning that they should for instance not ag...

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Detalles Bibliográficos
Autores principales: Basile, Walter, Sachenkova, Oxana, Light, Sara, Elofsson, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389847/
https://www.ncbi.nlm.nih.gov/pubmed/28355220
http://dx.doi.org/10.1371/journal.pcbi.1005375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389847/
https://www.ncbi.nlm.nih.gov/pubmed/28355220
http://dx.doi.org/10.1371/journal.pcbi.1005375

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