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High GC content causes orphan proteins to be intrinsically disordered
De novo creation of protein coding genes involves the formation of short ORFs from noncoding regions; some of these ORFs might then become fixed in the population. These orphan proteins need to, at the bare minimum, not cause serious harm to the organism, meaning that they should for instance not ag...
Autores principales: | Basile, Walter, Sachenkova, Oxana, Light, Sara, Elofsson, Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389847/ https://www.ncbi.nlm.nih.gov/pubmed/28355220 http://dx.doi.org/10.1371/journal.pcbi.1005375 |
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