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Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression

Thyroid cancer is common, yet the sequence of alterations that promote tumor formation are incompletely understood. Here, we describe a novel model of thyroid carcinoma in zebrafish that reveals temporal changes due to BRAF(V600E). Through the use of real-time in vivo imaging, we observe disruption...

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Detalles Bibliográficos
Autores principales:	Anelli, Viviana, Villefranc, Jacques A, Chhangawala, Sagar, Martinez-McFaline, Raul, Riva, Eleonora, Nguyen, Anvy, Verma, Akanksha, Bareja, Rohan, Chen, Zhengming, Scognamiglio, Theresa, Elemento, Olivier, Houvras, Yariv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389860/ https://www.ncbi.nlm.nih.gov/pubmed/28350298 http://dx.doi.org/10.7554/eLife.20728

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