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Major Depression and Acute Coronary Syndrome-Related Factors

BACKGROUND: Major Depressive Disorder (MDD) is one of the most common mental illnesses in psychiatry, being considered a risk factor for Acute Coronary Syndrome (ACS). OBJECTIVE: To assess the prevalence of MDD in ACS patients, as well as to analyze associated factors through the interdependence of...

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Autores principales: Figueiredo, Jose Henrique Cunha, Silva, Nelson Albuquerque de Souza e, Pereira, Basilio de Bragança, de Oliveira, Glaucia Maria Moraes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389871/
https://www.ncbi.nlm.nih.gov/pubmed/28443957
http://dx.doi.org/10.5935/abc.20170028
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author Figueiredo, Jose Henrique Cunha
Silva, Nelson Albuquerque de Souza e
Pereira, Basilio de Bragança
de Oliveira, Glaucia Maria Moraes
author_facet Figueiredo, Jose Henrique Cunha
Silva, Nelson Albuquerque de Souza e
Pereira, Basilio de Bragança
de Oliveira, Glaucia Maria Moraes
author_sort Figueiredo, Jose Henrique Cunha
collection PubMed
description BACKGROUND: Major Depressive Disorder (MDD) is one of the most common mental illnesses in psychiatry, being considered a risk factor for Acute Coronary Syndrome (ACS). OBJECTIVE: To assess the prevalence of MDD in ACS patients, as well as to analyze associated factors through the interdependence of sociodemographic, lifestyle and clinical variables. METHODS: Observational, descriptive, cross-sectional, case-series study conducted on patients hospitalized consecutively at the coronary units of three public hospitals in the city of Rio de Janeiro over a 24-month period. All participants answered a standardized questionnaire requesting sociodemographic, lifestyle and clinical data, as well as a structured diagnostic interview for the DSM-IV regarding ongoing major depressive episodes. A general log-linear model of multivariate analysis was employed to assess association and interdependence with a significance level of 5%. RESULTS: Analysis of 356 patients (229 men), with an average and median age of 60 years (SD ± 11.42, 27-89). We found an MDD point prevalence of 23%, and a significant association between MDD and gender, marital status, sedentary lifestyle, Killip classification, and MDD history. Controlling for gender, we found a statistically significant association between MDD and gender, age ≤ 60 years, sedentary lifestyle and MDD history. The log-linear model identified the variables MDD history, gender, sedentary lifestyle, and age ≤ 60 years as having the greatest association with MDD. CONCLUSION: Distinct approaches are required to diagnose and treat MDD in young women with ACS, history of MDD, sedentary lifestyle, and who are not in stable relationships.
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spelling pubmed-53898712017-04-18 Major Depression and Acute Coronary Syndrome-Related Factors Figueiredo, Jose Henrique Cunha Silva, Nelson Albuquerque de Souza e Pereira, Basilio de Bragança de Oliveira, Glaucia Maria Moraes Arq Bras Cardiol Original Articles BACKGROUND: Major Depressive Disorder (MDD) is one of the most common mental illnesses in psychiatry, being considered a risk factor for Acute Coronary Syndrome (ACS). OBJECTIVE: To assess the prevalence of MDD in ACS patients, as well as to analyze associated factors through the interdependence of sociodemographic, lifestyle and clinical variables. METHODS: Observational, descriptive, cross-sectional, case-series study conducted on patients hospitalized consecutively at the coronary units of three public hospitals in the city of Rio de Janeiro over a 24-month period. All participants answered a standardized questionnaire requesting sociodemographic, lifestyle and clinical data, as well as a structured diagnostic interview for the DSM-IV regarding ongoing major depressive episodes. A general log-linear model of multivariate analysis was employed to assess association and interdependence with a significance level of 5%. RESULTS: Analysis of 356 patients (229 men), with an average and median age of 60 years (SD ± 11.42, 27-89). We found an MDD point prevalence of 23%, and a significant association between MDD and gender, marital status, sedentary lifestyle, Killip classification, and MDD history. Controlling for gender, we found a statistically significant association between MDD and gender, age ≤ 60 years, sedentary lifestyle and MDD history. The log-linear model identified the variables MDD history, gender, sedentary lifestyle, and age ≤ 60 years as having the greatest association with MDD. CONCLUSION: Distinct approaches are required to diagnose and treat MDD in young women with ACS, history of MDD, sedentary lifestyle, and who are not in stable relationships. Sociedade Brasileira de Cardiologia - SBC 2017-03 /pmc/articles/PMC5389871/ /pubmed/28443957 http://dx.doi.org/10.5935/abc.20170028 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Figueiredo, Jose Henrique Cunha
Silva, Nelson Albuquerque de Souza e
Pereira, Basilio de Bragança
de Oliveira, Glaucia Maria Moraes
Major Depression and Acute Coronary Syndrome-Related Factors
title Major Depression and Acute Coronary Syndrome-Related Factors
title_full Major Depression and Acute Coronary Syndrome-Related Factors
title_fullStr Major Depression and Acute Coronary Syndrome-Related Factors
title_full_unstemmed Major Depression and Acute Coronary Syndrome-Related Factors
title_short Major Depression and Acute Coronary Syndrome-Related Factors
title_sort major depression and acute coronary syndrome-related factors
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389871/
https://www.ncbi.nlm.nih.gov/pubmed/28443957
http://dx.doi.org/10.5935/abc.20170028
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