T3SS-Independent Uptake of the Short-Trip Toxin-Related Recombinant NleC Effector of Enteropathogenic Escherichia coli Leads to NF-κB p65 Cleavage

Effector proteins secreted by the type 3 secretion system (T3SS) of pathogenic bacteria have been shown to precisely modulate important signaling cascades of the host for the benefit of the pathogens. Among others, the non-LEE encoded T3SS effector protein NleC of enteropathogenic Escherichia coli (...

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Detalles Bibliográficos
Autores principales: Stolle, Anne-Sophie, Norkowski, Stefanie, Körner, Britta, Schmitz, Jürgen, Lüken, Lena, Frankenberg, Maj, Rüter, Christian, Schmidt, M. Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390045/
https://www.ncbi.nlm.nih.gov/pubmed/28451521
http://dx.doi.org/10.3389/fcimb.2017.00119

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