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The catalytic role of the M2 metal ion in PP2Cα

PP2C family phosphatases (the type 2C family of protein phosphatases; or metal-dependent phosphatase, PPM) constitute an important class of signaling enzymes that regulate many fundamental life activities. All PP2C family members have a conserved binuclear metal ion active center that is essential f...

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Detalles Bibliográficos
Autores principales: Pan, Chang, Tang, Jun-yi, Xu, Yun-fei, Xiao, Peng, Liu, Hong-da, Wang, Hao-an, Wang, Wen-bo, Meng, Fan-guo, Yu, Xiao, Sun, Jin-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390078/
https://www.ncbi.nlm.nih.gov/pubmed/25708299
http://dx.doi.org/10.1038/srep08560