Cargando…

The catalytic role of the M2 metal ion in PP2Cα

PP2C family phosphatases (the type 2C family of protein phosphatases; or metal-dependent phosphatase, PPM) constitute an important class of signaling enzymes that regulate many fundamental life activities. All PP2C family members have a conserved binuclear metal ion active center that is essential f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Chang, Tang, Jun-yi, Xu, Yun-fei, Xiao, Peng, Liu, Hong-da, Wang, Hao-an, Wang, Wen-bo, Meng, Fan-guo, Yu, Xiao, Sun, Jin-peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390078/ https://www.ncbi.nlm.nih.gov/pubmed/25708299 http://dx.doi.org/10.1038/srep08560

Ejemplares similares

Metal-free catalytic hydrocarboxylation of hexafluorobut-2-yne
por: Zeng, Ji-Jun, et al.
Publicado: (2021)

Effect of metal ions on Alzheimer's disease
por: Liu, Fan, et al.
Publicado: (2022)

Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP–2A in mouse eye
por: Liu, Wen-Bin, et al.
Publicado: (2008)

Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A
por: Hoermann, Bernhard, et al.
Publicado: (2020)

Catalytic Cleavage of the C-O Bond in 2,6-dimethoxyphenol Without External Hydrogen or Organic Solvent Using Catalytic Vanadium Metal
por: Yu, Peng, et al.
Publicado: (2020)

Controlling Thermal Expansion Behaviors of Fence-Like Metal-Organic Frameworks by Varying/Mixing Metal Ions
por: Zhou, Hao-Long, et al.
Publicado: (2018)

Comprehensive analysis of tumor necrosis factor-α-inducible protein 8-like 2 (TIPE2): A potential novel pan-cancer immune checkpoint
por: Bai, Kun-Hao, et al.
Publicado: (2022)

Hepatocyte-Specific Ablation of PP2A Catalytic Subunit α Attenuates Liver Fibrosis Progression via TGF-β1/Smad Signaling
por: Lu, Na, et al.
Publicado: (2015)

Interface catalytic regulation via electron rearrangement and hydroxyl radicals triggered by oxygen vacancies and heavy metal ions
por: Xiao, Xiang-Yu, et al.
Publicado: (2023)

Functional Identification of Catalytic Metal Ion Binding Sites within RNA
por: Hougland, James L, et al.
Publicado: (2005)

The structure of a nucleolytic ribozyme that employs a catalytic metal ion
por: Liu, Yijin, et al.
Publicado: (2017)

Protein Phosphatase 2A Catalytic Subunit PP2A-1 Enhances Rice Resistance to Sheath Blight Disease
por: Lin, Qiu Jun, et al.
Publicado: (2021)

Metal ions shape α-synuclein
por: Moons, Rani, et al.
Publicado: (2020)

More precise prediction in Chinese patients with penile squamous cell carcinoma: protein kinase CK2α catalytic subunit (CK2α) as a poor prognosticator
por: Li, Zai-Shang, et al.
Publicado: (2017)

The Goldfish SG2NA Gene Encodes Two α-Type Regulatory Subunits for PP-2A and Displays Distinct Developmental Expression Pattern
por: Ma, Hai-Li, et al.
Publicado: (2009)

Electromagnetic Interference Shielding of 2D Transition Metal Carbide (MXene)/Metal Ion Composites
por: Xia, Xuefeng, et al.
Publicado: (2021)

Sonochemical preparation of polymer–metal nanocomposites with catalytic and plasmonic properties
por: Wan, Jing, et al.
Publicado: (2021)

Oxidase-Like Catalytic Performance of Nano-MnO(2) and Its Potential Application for Metal Ions Detection in Water
por: Sun, Kai, et al.
Publicado: (2019)

Protein kinase CK2α catalytic subunit is overexpressed and serves as an unfavorable prognostic marker in primary hepatocellular carcinoma
por: Zhang, Hong-Xia, et al.
Publicado: (2015)

Six metal–organic architectures from a 5-methoxyisophthalate linker: assembly, structural variety and catalytic features
por: Fan, Xiao-Xiang, et al.
Publicado: (2023)

Overexpression of PpSnRK1α in Tomato Promotes Fruit Ripening by Enhancing RIPENING INHIBITOR Regulation Pathway
por: Yu, Wen, et al.
Publicado: (2018)

The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes
por: Wang, Hong-Mei, et al.
Publicado: (2014)

Catalytic Conversion of Cellulose to Levulinic Acid by Metal Chlorides
por: Peng, Lincai, et al.
Publicado: (2010)

Molecular Mechanism of PP2A/B55α Inhibition by IER5
por: Cao, Ruili, et al.
Publicado: (2023)

Recent Advances in Catalytic Oxidation of Organic Sulfides: Applications of Metal–Ionic Liquid Catalytic Systems
por: Liu, Xiao Bing, et al.
Publicado: (2022)

Self-Enhanced Catalytic Activity of Pt/TiO(2) via Electronic Metal–Support Interaction
por: Tian, Shuheng, et al.
Publicado: (2023)

Novel Metal Nanomaterials and Their Catalytic Applications
por: Wang, Jiaqing, et al.
Publicado: (2015)

Transcriptional Regulation of PP2A-Aα Is Mediated by Multiple Factors Including AP-2α, CREB, ETS-1, and SP-1
por: Chen, He-Ge, et al.
Publicado: (2009)

Role of cantharidin in the activation of IKKα/IκBα/NF-κB pathway by inhibiting PP2A activity in cholangiocarcinoma cell lines
por: Zhou, Huijiang, et al.
Publicado: (2018)

In situ catalytic growth of large-area multilayered graphene/MoS(2) heterostructures
por: Fu, Wei, et al.
Publicado: (2014)

Metal 3D printing technology for functional integration of catalytic system
por: Wei, Qinhong, et al.
Publicado: (2020)

Liver PP2A-Cα Protects From Parenteral Nutrition-associated Hepatic Steatosis
por: Maitiabula, Gulisudumu, et al.
Publicado: (2022)

Enhancing Catalytic Activity and Selectivity by Plasmon-Induced Hot Carriers
por: Liu, Xiao-Qing, et al.
Publicado: (2020)

Overexpression of PpSnRK1α in Tomato Increased Autophagy Activity under Low Nutrient Stress
por: Luo, Jingjing, et al.
Publicado: (2022)

Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism
por: Zhao, Haiyan, et al.
Publicado: (2015)

Enantioselective Catalytic Synthesis of α-Halogenated α-Aryl-β(2,2)-amino Acid Derivatives
por: Zebrowski, Paul, et al.
Publicado: (2021)

Recent Advances in Antimicrobial Hydrogels Containing Metal Ions and Metals/Metal Oxide Nanoparticles
por: Wahid, Fazli, et al.
Publicado: (2017)

Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells
por: Zonta, Francesca, et al.
Publicado: (2021)

CO(2) Cycloaddition to Epoxides by using M‐DABCO Metal–Organic Frameworks and the Influence of the Synthetic Method on Catalytic Reactivity
por: Mousavi, Bibimaryam, et al.
Publicado: (2017)

Strategies for the application of metal–organic frameworks in catalytic reactions
por: Gao, Fei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_k1b7a7dnr1e09qk4frr0o3uhad