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Identification of Three Early Phases of Cell-Fate Determination during Osteogenic and Adipogenic Differentiation by Transcription Factor Dynamics

Age-related skeletal degeneration in patients with osteoporosis is characterized by decreased bone mass and occurs concomitant with an increase in bone marrow adipocytes. Using microarray expression profiling with high temporal resolution, we identified gene regulatory events in early stages of oste...

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Detalles Bibliográficos
Autores principales: van de Peppel, Jeroen, Strini, Tanja, Tilburg, Julia, Westerhoff, Hans, van Wijnen, Andre J., van Leeuwen, Johannes P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390132/
https://www.ncbi.nlm.nih.gov/pubmed/28344004
http://dx.doi.org/10.1016/j.stemcr.2017.02.018

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