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Identification of Three Early Phases of Cell-Fate Determination during Osteogenic and Adipogenic Differentiation by Transcription Factor Dynamics
Age-related skeletal degeneration in patients with osteoporosis is characterized by decreased bone mass and occurs concomitant with an increase in bone marrow adipocytes. Using microarray expression profiling with high temporal resolution, we identified gene regulatory events in early stages of oste...
Autores principales: | van de Peppel, Jeroen, Strini, Tanja, Tilburg, Julia, Westerhoff, Hans, van Wijnen, Andre J., van Leeuwen, Johannes P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390132/ https://www.ncbi.nlm.nih.gov/pubmed/28344004 http://dx.doi.org/10.1016/j.stemcr.2017.02.018 |
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