Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells

In vitro models of the human blood-brain barrier (BBB) are highly desirable for drug development. This study aims to analyze a set of ten different BBB culture models based on primary cells, human induced pluripotent stem cells (hiPSCs), and multipotent fetal neural stem cells (fNSCs). We systematic...

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Detalles Bibliográficos
Autores principales: Appelt-Menzel, Antje, Cubukova, Alevtina, Günther, Katharina, Edenhofer, Frank, Piontek, Jörg, Krause, Gerd, Stüber, Tanja, Walles, Heike, Neuhaus, Winfried, Metzger, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390136/
https://www.ncbi.nlm.nih.gov/pubmed/28344002
http://dx.doi.org/10.1016/j.stemcr.2017.02.021

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