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Rhinocerebral Mucormycosis: Report of a Rare Case

BACKGROUND: Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manif...

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Autores principales: Sahota, Richa, Gambhir, Ramandeep, Anand, Samir, Dixit, Avani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Publications Office of Jimma University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390232/
https://www.ncbi.nlm.nih.gov/pubmed/28458494
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author Sahota, Richa
Gambhir, Ramandeep
Anand, Samir
Dixit, Avani
author_facet Sahota, Richa
Gambhir, Ramandeep
Anand, Samir
Dixit, Avani
author_sort Sahota, Richa
collection PubMed
description BACKGROUND: Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manifests as rhinocerebral, pulmonary, gastrointestinal, cutaneous or disseminated form. The underlying conditions can influence clinical presentation and often delay diagnosis, with resultant poor outcomes. CASE DETAILS: We report a case of rhinocerebral mucormycosis in a 75 year-old diabetic patient with emphasise on diagnosis, treatment and survival options of patient from this potentially fatal fungal infection. Extra oral examination revealed mild non-tender swelling on the face, unable to see from left eye, impaired sense of smell, difficulty in speech and nasal stuffiness. Intra-oral examination showed necrosis of mucosa and underlying bone in relation to canine to the tuberosity area of the left vestibular region of the maxilla. CONCLUSION: Timely diagnosis is critical to survival and minimization of morbidity. Institution of surgical and medical therapy is critical in maximizing the likelihood of good outcome.
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spelling pubmed-53902322017-04-28 Rhinocerebral Mucormycosis: Report of a Rare Case Sahota, Richa Gambhir, Ramandeep Anand, Samir Dixit, Avani Ethiop J Health Sci Case Report BACKGROUND: Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manifests as rhinocerebral, pulmonary, gastrointestinal, cutaneous or disseminated form. The underlying conditions can influence clinical presentation and often delay diagnosis, with resultant poor outcomes. CASE DETAILS: We report a case of rhinocerebral mucormycosis in a 75 year-old diabetic patient with emphasise on diagnosis, treatment and survival options of patient from this potentially fatal fungal infection. Extra oral examination revealed mild non-tender swelling on the face, unable to see from left eye, impaired sense of smell, difficulty in speech and nasal stuffiness. Intra-oral examination showed necrosis of mucosa and underlying bone in relation to canine to the tuberosity area of the left vestibular region of the maxilla. CONCLUSION: Timely diagnosis is critical to survival and minimization of morbidity. Institution of surgical and medical therapy is critical in maximizing the likelihood of good outcome. Research and Publications Office of Jimma University 2017-01 /pmc/articles/PMC5390232/ /pubmed/28458494 Text en Copyright © Jimma University, Research & Publications Office 2017 This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Sahota, Richa
Gambhir, Ramandeep
Anand, Samir
Dixit, Avani
Rhinocerebral Mucormycosis: Report of a Rare Case
title Rhinocerebral Mucormycosis: Report of a Rare Case
title_full Rhinocerebral Mucormycosis: Report of a Rare Case
title_fullStr Rhinocerebral Mucormycosis: Report of a Rare Case
title_full_unstemmed Rhinocerebral Mucormycosis: Report of a Rare Case
title_short Rhinocerebral Mucormycosis: Report of a Rare Case
title_sort rhinocerebral mucormycosis: report of a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390232/
https://www.ncbi.nlm.nih.gov/pubmed/28458494
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