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Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo

Astrocytes from familial amyotrophic lateral sclerosis (ALS) patients or transgenic mice are toxic specifically to motor neurons (MNs). It is not known if astrocytes from sporadic ALS (sALS) patients cause MN degeneration in vivo and whether the effect is specific to MNs. By transplanting spinal neu...

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Detalles Bibliográficos
Autores principales:	Qian, Kun, Huang, Hailong, Peterson, Andrew, Hu, Baoyang, Maragakis, Nicholas J., Ming, Guo-li, Chen, Hong, Zhang, Su-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390239/ https://www.ncbi.nlm.nih.gov/pubmed/28366455 http://dx.doi.org/10.1016/j.stemcr.2017.03.003

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