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T-Bet independent development of IFNγ secreting natural T helper 1 cell population in the absence of Itk

Th1, Th2, Th9 and Th17 cells are conventional CD4(+) effector T cells identified as secretors of prototypical cytokines IFNγ, IL4, IL9, and IL-17A respectively. Recently, populations of natural Th17 and Th1 cells (nTh17 and nTh1) with innate-like phenotype have been identified in the thymus that are...

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Detalles Bibliográficos
Autores principales: Kannan, Arun K., Mohinta, Sonia, Huang, Weishan, Huang, Lu, Koylass, Nicholas, Appleton, Judith A., August, Avery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390256/
https://www.ncbi.nlm.nih.gov/pubmed/28406139
http://dx.doi.org/10.1038/srep45935

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