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Differential adipokine DNA methylation and gene expression in subcutaneous adipose tissue from adult offspring of women with diabetes in pregnancy

BACKGROUND: Offspring of women with diabetes in pregnancy are at increased risk of type 2 diabetes mellitus (T2DM), potentially mediated by epigenetic mechanisms. The adipokines leptin, adiponectin, and resistin (genes: LEP, ADIPOQ, RETN) play key roles in the pathophysiology of T2DM. We hypothesize...

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Detalles Bibliográficos
Autores principales:	Houshmand-Oeregaard, Azadeh, Hansen, Ninna S., Hjort, Line, Kelstrup, Louise, Broholm, Christa, Mathiesen, Elisabeth R., Clausen, Tine D., Damm, Peter, Vaag, Allan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390345/ https://www.ncbi.nlm.nih.gov/pubmed/28413567 http://dx.doi.org/10.1186/s13148-017-0338-2

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