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The PD-1: PD-L1 pathway promotes development of brain-resident memory T cells following acute viral encephalitis
BACKGROUND: Previous work from our laboratory has demonstrated that during acute viral brain infection, glial cells modulate antiviral T cell effector responses through the PD-1: PD-L1 pathway, thereby limiting the deleterious consequences of unrestrained neuroinflammation. Here, we evaluated the PD...
Autores principales: | Prasad, Sujata, Hu, Shuxian, Sheng, Wen S., Chauhan, Priyanka, Singh, Amar, Lokensgard, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390367/ https://www.ncbi.nlm.nih.gov/pubmed/28407741 http://dx.doi.org/10.1186/s12974-017-0860-3 |
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