Glucose-regulated protein 78 demonstrates antiviral effects but is more suitable for hepatocellular carcinoma prevention in hepatitis B

BACKGROUND: Hepatitis B virus (HBV) is the leading cause of liver cirrhosis and hepatocellular carcinoma in Asia and Africa. Existing antivirals cannot cure HBV or eliminate risk of hepatocellular carcinoma. Glucose-regulated protein 78 (GRP78) can inhibit HBV replication, but promote virion secreti...

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Detalles Bibliográficos
Autores principales: Zheng, Nai Q., Zheng, Zi H., Xu, Hai X., Huang, Ming X., Peng, Xiao M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390389/
https://www.ncbi.nlm.nih.gov/pubmed/28407787
http://dx.doi.org/10.1186/s12985-017-0747-z

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