Cargando…

Large enchondroma of the thoracic spine: a rare case report and review of the literature

BACKGROUND: Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Jing, Gao, Ju-zhou, Guo, Lian-jin, Yin, Zhi-xun, He, Er-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390427/
https://www.ncbi.nlm.nih.gov/pubmed/28407736
http://dx.doi.org/10.1186/s12891-017-1519-z
_version_ 1782521458296094720
author Guo, Jing
Gao, Ju-zhou
Guo, Lian-jin
Yin, Zhi-xun
He, Er-xing
author_facet Guo, Jing
Gao, Ju-zhou
Guo, Lian-jin
Yin, Zhi-xun
He, Er-xing
author_sort Guo, Jing
collection PubMed
description BACKGROUND: Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma in the thoracic spine of a 49-year-old woman, and discuss its clinical, radiological and histopathological characteristics. CASE PRESENTATION: The patient presented with rapidly progressive and severe pain on her upper back. Magnetic resonance imaging revealed an expansile lesion at the posterior elements of T3 that was hypointense on T1-weighted images and mixed iso- to hyperintense on T2-weighted images. Administration of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) resulted in heterogeneous enhancement. During surgery, a large tumor of 4.2cm × 4.7cm × 2.1cm was resected along with the lamina and spinous process. Histological examination revealed that the tumor consisted of mature hyaline cartilage with typical chondrocytes, indicating that it was an enchondroma. CONCLUSIONS: Despite its benign-growing nature, enchondroma should be examined closely for signs of enchondromatosis and enchondrosarcoma. Complete surgical resection is the treatment of choice for immediate relief of symptoms and avoidance of recurrence.
format Online
Article
Text
id pubmed-5390427
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-53904272017-04-14 Large enchondroma of the thoracic spine: a rare case report and review of the literature Guo, Jing Gao, Ju-zhou Guo, Lian-jin Yin, Zhi-xun He, Er-xing BMC Musculoskelet Disord Case Report BACKGROUND: Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma in the thoracic spine of a 49-year-old woman, and discuss its clinical, radiological and histopathological characteristics. CASE PRESENTATION: The patient presented with rapidly progressive and severe pain on her upper back. Magnetic resonance imaging revealed an expansile lesion at the posterior elements of T3 that was hypointense on T1-weighted images and mixed iso- to hyperintense on T2-weighted images. Administration of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) resulted in heterogeneous enhancement. During surgery, a large tumor of 4.2cm × 4.7cm × 2.1cm was resected along with the lamina and spinous process. Histological examination revealed that the tumor consisted of mature hyaline cartilage with typical chondrocytes, indicating that it was an enchondroma. CONCLUSIONS: Despite its benign-growing nature, enchondroma should be examined closely for signs of enchondromatosis and enchondrosarcoma. Complete surgical resection is the treatment of choice for immediate relief of symptoms and avoidance of recurrence. BioMed Central 2017-04-13 /pmc/articles/PMC5390427/ /pubmed/28407736 http://dx.doi.org/10.1186/s12891-017-1519-z Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Guo, Jing
Gao, Ju-zhou
Guo, Lian-jin
Yin, Zhi-xun
He, Er-xing
Large enchondroma of the thoracic spine: a rare case report and review of the literature
title Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_full Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_fullStr Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_full_unstemmed Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_short Large enchondroma of the thoracic spine: a rare case report and review of the literature
title_sort large enchondroma of the thoracic spine: a rare case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390427/
https://www.ncbi.nlm.nih.gov/pubmed/28407736
http://dx.doi.org/10.1186/s12891-017-1519-z
work_keys_str_mv AT guojing largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature
AT gaojuzhou largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature
AT guolianjin largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature
AT yinzhixun largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature
AT heerxing largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature