Cargando…
Large enchondroma of the thoracic spine: a rare case report and review of the literature
BACKGROUND: Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390427/ https://www.ncbi.nlm.nih.gov/pubmed/28407736 http://dx.doi.org/10.1186/s12891-017-1519-z |
_version_ | 1782521458296094720 |
---|---|
author | Guo, Jing Gao, Ju-zhou Guo, Lian-jin Yin, Zhi-xun He, Er-xing |
author_facet | Guo, Jing Gao, Ju-zhou Guo, Lian-jin Yin, Zhi-xun He, Er-xing |
author_sort | Guo, Jing |
collection | PubMed |
description | BACKGROUND: Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma in the thoracic spine of a 49-year-old woman, and discuss its clinical, radiological and histopathological characteristics. CASE PRESENTATION: The patient presented with rapidly progressive and severe pain on her upper back. Magnetic resonance imaging revealed an expansile lesion at the posterior elements of T3 that was hypointense on T1-weighted images and mixed iso- to hyperintense on T2-weighted images. Administration of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) resulted in heterogeneous enhancement. During surgery, a large tumor of 4.2cm × 4.7cm × 2.1cm was resected along with the lamina and spinous process. Histological examination revealed that the tumor consisted of mature hyaline cartilage with typical chondrocytes, indicating that it was an enchondroma. CONCLUSIONS: Despite its benign-growing nature, enchondroma should be examined closely for signs of enchondromatosis and enchondrosarcoma. Complete surgical resection is the treatment of choice for immediate relief of symptoms and avoidance of recurrence. |
format | Online Article Text |
id | pubmed-5390427 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-53904272017-04-14 Large enchondroma of the thoracic spine: a rare case report and review of the literature Guo, Jing Gao, Ju-zhou Guo, Lian-jin Yin, Zhi-xun He, Er-xing BMC Musculoskelet Disord Case Report BACKGROUND: Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchondroma have been reported. The authors document a rare case of large enchondroma in the thoracic spine of a 49-year-old woman, and discuss its clinical, radiological and histopathological characteristics. CASE PRESENTATION: The patient presented with rapidly progressive and severe pain on her upper back. Magnetic resonance imaging revealed an expansile lesion at the posterior elements of T3 that was hypointense on T1-weighted images and mixed iso- to hyperintense on T2-weighted images. Administration of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) resulted in heterogeneous enhancement. During surgery, a large tumor of 4.2cm × 4.7cm × 2.1cm was resected along with the lamina and spinous process. Histological examination revealed that the tumor consisted of mature hyaline cartilage with typical chondrocytes, indicating that it was an enchondroma. CONCLUSIONS: Despite its benign-growing nature, enchondroma should be examined closely for signs of enchondromatosis and enchondrosarcoma. Complete surgical resection is the treatment of choice for immediate relief of symptoms and avoidance of recurrence. BioMed Central 2017-04-13 /pmc/articles/PMC5390427/ /pubmed/28407736 http://dx.doi.org/10.1186/s12891-017-1519-z Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Guo, Jing Gao, Ju-zhou Guo, Lian-jin Yin, Zhi-xun He, Er-xing Large enchondroma of the thoracic spine: a rare case report and review of the literature |
title | Large enchondroma of the thoracic spine: a rare case report and review of the literature |
title_full | Large enchondroma of the thoracic spine: a rare case report and review of the literature |
title_fullStr | Large enchondroma of the thoracic spine: a rare case report and review of the literature |
title_full_unstemmed | Large enchondroma of the thoracic spine: a rare case report and review of the literature |
title_short | Large enchondroma of the thoracic spine: a rare case report and review of the literature |
title_sort | large enchondroma of the thoracic spine: a rare case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390427/ https://www.ncbi.nlm.nih.gov/pubmed/28407736 http://dx.doi.org/10.1186/s12891-017-1519-z |
work_keys_str_mv | AT guojing largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature AT gaojuzhou largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature AT guolianjin largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature AT yinzhixun largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature AT heerxing largeenchondromaofthethoracicspineararecasereportandreviewoftheliterature |