Novel lead structures with both Plasmodium falciparum gametocytocidal and asexual blood stage activity identified from high throughput compound screening

BACKGROUND: Blocking malaria transmission is an important step in eradicating malaria. In the field, transmission requires the production of sexual stage Plasmodium parasites, called gametocytes, which are not effectively killed by the commonly used anti-malarials allowing individuals to remain infe...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Huang, Xiuli, Li, Hao, Tawa, Gregory, Fisher, Ethan, Tanaka, Takeshi Q., Shinn, Paul, Huang, Wenwei, Williamson, Kim C., Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390467/
https://www.ncbi.nlm.nih.gov/pubmed/28407766
http://dx.doi.org/10.1186/s12936-017-1805-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390467/
https://www.ncbi.nlm.nih.gov/pubmed/28407766
http://dx.doi.org/10.1186/s12936-017-1805-0

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