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Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance
For over four decades structural biology has been used to understand the mechanisms of disease, and structure-guided approaches have demonstrated clearly that they can contribute to many aspects of early drug discovery, both computationally and experimentally. Structure can also inform our understan...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390495/ https://www.ncbi.nlm.nih.gov/pubmed/28408471 http://dx.doi.org/10.1042/BST20160422 |