Cargando…

Transcription-Based Prediction of Response to IFNβ Using Supervised Computational Methods

Changes in cellular functions in response to drug therapy are mediated by specific transcriptional profiles resulting from the induction or repression in the activity of a number of genes, thereby modifying the preexisting gene activity pattern of the drug-targeted cell(s). Recombinant human interfe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baranzini, Sergio E, Mousavi, Parvin, Rio, Jordi, Caillier, Stacy J, Stillman, Althea, Villoslada, Pablo, Wyatt, Matthew M, Comabella, Manuel, Greller, Larry D, Somogyi, Roland, Montalban, Xavier, Oksenberg, Jorge R
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539058/ https://www.ncbi.nlm.nih.gov/pubmed/15630474 http://dx.doi.org/10.1371/journal.pbio.0030002

Ejemplares similares

Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset
por: Khankhanian, Pouya, et al.
Publicado: (2010)

Search for Specific Biomarkers of IFNβ Bioactivity in Patients with Multiple Sclerosis
por: Malhotra, Sunny, et al.
Publicado: (2011)

Baseline Gene Expression Signatures in Monocytes from Multiple Sclerosis Patients Treated with Interferon-beta
por: Bustamante, Marta F., et al.
Publicado: (2013)

SNP imputation bias reduces effect size determination
por: Khankhanian, Pouya, et al.
Publicado: (2015)

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β
por: Bustamante, Marta F., et al.
Publicado: (2015)

Increased NLRP3 Inflammasome Activation and Pyroptosis in Patients With Multiple Sclerosis With Fingolimod Treatment Failure
por: Malhotra, Sunny, et al.
Publicado: (2023)

Identification of a Novel Risk Locus for Multiple Sclerosis at 13q31.3 by a Pooled Genome-Wide Scan of 500,000 Single Nucleotide Polymorphisms
por: Comabella, Manuel, et al.
Publicado: (2008)

Copy number variation in African Americans
por: McElroy, Joseph P, et al.
Publicado: (2009)

iCTNet: A Cytoscape plugin to produce and analyze integrative complex traits networks
por: Wang, Lili, et al.
Publicado: (2011)

Chitinases and chitinase-like proteins as biomarkers in neurologic disorders
por: Pinteac, Rucsanda, et al.
Publicado: (2020)

The killer immunoglobulin-like receptor KIR3DL1 combination with HLA-Bw4 is protective against multiple sclerosis in African Americans
por: Hollenbach, Jill A., et al.
Publicado: (2016)

Serum Levels of CXCL13 Are Associated With Teriflunomide Response in Patients With Multiple Sclerosis
por: Fissolo, Nicolás, et al.
Publicado: (2022)

iCTNet2: integrating heterogeneous biological interactions to understand complex traits
por: Wang, Lili, et al.
Publicado: (2015)

Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis
por: Jia, Xiaoming, et al.
Publicado: (2018)

Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression
por: Barbour, Jason D, et al.
Publicado: (2007)

Correction: Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression
por: Barbour, Jason D, et al.
Publicado: (2007)

Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis
por: Didonna, Alessandro, et al.
Publicado: (2016)

Specific hypomethylation programs underpin B cell activation in early multiple sclerosis
por: Ma, Qin, et al.
Publicado: (2021)

Opposite Roles of NMDA Receptors in Relapsing and Primary Progressive Multiple Sclerosis
por: Rossi, Silvia, et al.
Publicado: (2013)

Liquid Biopsy in Neurological Diseases
por: Malhotra, Sunny, et al.
Publicado: (2023)

Metabolomic signatures associated with disease severity in multiple sclerosis
por: Villoslada, Pablo, et al.
Publicado: (2017)

Circulating EZH2-positive T cells are decreased in multiple sclerosis patients
por: Malhotra, Sunny, et al.
Publicado: (2018)

The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse
por: Pedemonte, Enrico, et al.
Publicado: (2007)

Cladribine tablets added to IFN-β in active relapsing MS: The ONWARD study
por: Montalban, Xavier, et al.
Publicado: (2018)

Integration of epigenetic and genetic profiles identifies multiple sclerosis disease-critical cell types and genes
por: Ma, Qin, et al.
Publicado: (2023)

Detection of identity by descent using next-generation whole genome sequencing data
por: Su, Shu-Yi, et al.
Publicado: (2012)

Immunomodulatory Effects Associated with Cladribine Treatment
por: Fissolo, Nicolás, et al.
Publicado: (2021)

Risk Acceptance in Multiple Sclerosis Patients on Natalizumab Treatment
por: Tur, Carmen, et al.
Publicado: (2013)

Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis
por: Didonna, Alessandro, et al.
Publicado: (2020)

In depth comparison of an individual’s DNA and its lymphoblastoid cell line using whole genome sequencing
por: Nickles, Dorothee, et al.
Publicado: (2012)

Prediction of Graft-Versus-Host Disease in Humans by Donor Gene-Expression Profiling
por: Baron, Chantal, et al.
Publicado: (2007)

Role of high mobility group box protein 1 (HMGB1) in peripheral blood from patients with multiple sclerosis
por: Malhotra, Sunny, et al.
Publicado: (2015)

Native ancestry is associated with optic neuritis and age of onset in hispanics with multiple sclerosis
por: Amezcua, Lilyana, et al.
Publicado: (2018)

Chitinase 3-like 1 is neurotoxic in primary cultured neurons
por: Matute-Blanch, Clara, et al.
Publicado: (2020)

Lesion topographies in multiple sclerosis diagnosis: A reappraisal
por: Arrambide, Georgina, et al.
Publicado: (2017)

High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility
por: Osoegawa, Kazutoyo, et al.
Publicado: (2021)

Optic Nerve Topography in Multiple Sclerosis Diagnosis: The Utility of Visual Evoked Potentials
por: Vidal-Jordana, Angela, et al.
Publicado: (2021)

Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity
por: Dunn, Shannon E., et al.
Publicado: (2007)

Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity
por: Dunn, Shannon E., et al.
Publicado: (2007)

Correction: Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity
por: Dunn, Shannon E., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_48pt6htuvqmtu8m28ofb61mf8n