Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma

Intraocular pressure (IOP) is maintained as a result of the balance between production of aqueous humour (AH) by the ciliary processes and hydrodynamic resistance to its outflow through the conventional outflow pathway comprising the trabecular meshwork (TM) and Schlemm’s canal (SC). Elevated IOP, w...

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Detalles Bibliográficos
Autores principales: O’Callaghan, Jeffrey, Crosbie, Darragh. E., Cassidy, Paul. S., Sherwood, Joseph M., Flügel-Koch, Cassandra, Lütjen-Drecoll, Elke, Humphries, Marian M., Reina-Torres, Ester, Wallace, Deborah, Kiang, Anna-Sophia, Campbell, Matthew, Stamer, W. Daniel, Overby, Darryl R., O’Brien, Colm, Tam, Lawrence C. S., Humphries, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390678/
https://www.ncbi.nlm.nih.gov/pubmed/28158775
http://dx.doi.org/10.1093/hmg/ddx028

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