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Engineering proximal vs. distal heme–NO coordination via dinitrosyl dynamics: implications for NO sensor design

Proximal vs. distal heme–NO coordination is a novel strategy for selective gas response in heme-based NO-sensors. In the case of Alcaligenes xylosoxidans cytochrome c′ (AXCP), formation of a transient distal 6cNO complex is followed by scission of the trans Fe–His bond and conversion to a proximal 5...

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Detalles Bibliográficos
Autores principales:	Kekilli, Demet, Petersen, Christine A., Pixton, David A., Ghafoor, Dlzar D., Abdullah, Gaylany H., Dworkowski, Florian S. N., Wilson, Michael T., Heyes, Derren J., Hardman, Samantha J. O., Murphy, Loretta M., Strange, Richard W., Scrutton, Nigel S., Andrew, Colin R., Hough, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390784/ https://www.ncbi.nlm.nih.gov/pubmed/28451315 http://dx.doi.org/10.1039/c6sc04190f

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