Synthesis of C (2)‐Symmetric Diphosphormonoamidites and Their Use as Ligands in Rh‐Catalyzed Hydroformylation: Relationships between Activity and Hydrolysis Stability

A series of diphosphoramidites has been synthetized with a piperazine, homopiperazine, and an acyclic 1,2‐diamine unit in the backbone. New compounds were tested alongside related N‐acyl phosphoramidites as ligands in the Rh‐catalyzed hydroformylation of n‐octenes to investigate their influence on t...

Descripción completa

Detalles Bibliográficos
Autores principales: Morales Torres, Galina, Behrens, Stephan, Michalik, Dirk, Selent, Detlef, Spannenberg, Anke, Lühr, Susan, Dyballa, Katrin Marie, Franke, Robert, Börner, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390800/
https://www.ncbi.nlm.nih.gov/pubmed/28413760
http://dx.doi.org/10.1002/open.201600152
Descripción
Sumario:A series of diphosphoramidites has been synthetized with a piperazine, homopiperazine, and an acyclic 1,2‐diamine unit in the backbone. New compounds were tested alongside related N‐acyl phosphoramidites as ligands in the Rh‐catalyzed hydroformylation of n‐octenes to investigate their influence on the activity and regioselectivity. A subsequent study of their hydrolysis stability revealed that the most stable ligands induced the highest activity in the catalytic reaction.

Ejemplares similares