Cargando…
Variation within MBP gene predicts disease course in multiple sclerosis
OBJECTIVE: Prognosis following a first demyelinating event is difficult to predict, with no genetic markers of MS progression currently identified. Myelin basic protein (MBP) is a major component of the myelin sheath of CNS neurons and may play a central role in demyelinating diseases such as MS. Ho...
Autores principales: | Zhou, Yuan, Simpson, Steve, Charlesworth, Jac C., van der Mei, Ingrid, Lucas, Robyn M., Ponsonby, Anne‐Louise, Taylor, Bruce V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390844/ https://www.ncbi.nlm.nih.gov/pubmed/28413712 http://dx.doi.org/10.1002/brb3.670 |
Ejemplares similares
-
Sun Exposure across the Life Course Significantly Modulates Early Multiple Sclerosis Clinical Course
por: Simpson, Steve, et al.
Publicado: (2018) -
Developing a clinical–environmental–genotypic prognostic index for relapsing-onset multiple sclerosis and clinically isolated syndrome
por: Fuh-Ngwa, Valery, et al.
Publicado: (2021) -
Onset Symptoms, Tobacco Smoking, and Progressive-Onset Phenotype Are Associated With a Delayed Onset of Multiple Sclerosis, and Marijuana Use With an Earlier Onset
por: Tao, Chunrong, et al.
Publicado: (2018) -
Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis
por: Fuh-Ngwa, Valery, et al.
Publicado: (2022) -
Predictors of progression from a first demyelinating event to clinically definite multiple sclerosis
por: Chapman, Caron, et al.
Publicado: (2022)