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Early dissemination seeds metastasis in breast cancer

Accumulating data suggest that metastatic dissemination often occurs early during tumour formation but the mechanisms of early metastatic spread have not yet been addressed. Here, we studied metastasis in a HER2-driven mouse breast cancer model and found that progesterone-induced signalling triggere...

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Detalles Bibliográficos
Autores principales: Hosseini, Hedayatollah, Obradović, Milan M.S., Hoffmann, Martin, Harper, Kathryn, Sosa, Maria Soledad, Werner-Klein, Melanie, Nanduri, Lahiri Kanth, Werno, Christian, Ehrl, Carolin, Maneck, Matthias, Patwary, Nina, Haunschild, Gundula, Gužvić, Miodrag, Reimelt, Christian, Grauvogl, Michael, Eichner, Norbert, Weber, Florian, Hartkopf, Andreas, Taran, Florin-Andrei, Brucker, Sara Y., Fehm, Tanja, Rack, Brigitte, Buchholz, Stefan, Spang, Rainer, Meister, Gunter, Aguirre-Ghiso, Julio A., Klein, Christoph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390864/
https://www.ncbi.nlm.nih.gov/pubmed/27974799
http://dx.doi.org/10.1038/nature20785

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