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Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection

Human cytomegalovirus (CMV) infection is a substantial cause of morbidity and mortality in immunocompromised hosts and globally is one of the most important congenital infections. The nucleoside analogue ganciclovir (GCV), which requires initial phosphorylation by the viral UL97 kinase, is the mains...

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Detalles Bibliográficos
Autores principales:	Rose, Jessica, Emery, Vincent C., Kumar, Deepali, Asberg, Anders, Hartmann, Anders, Jardine, Alan G., Bignamini, Angelo A., Humar, Atul, Neumann, Avidan U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391089/ https://www.ncbi.nlm.nih.gov/pubmed/28406982 http://dx.doi.org/10.1371/journal.ppat.1006299

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