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Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes

Genome-wide association studies (GWAS) have linked dozens of single nucleotide polymorphisms (SNPs) with Parkinson’s disease (PD) risk. Ascertaining the functional and eventual causal mechanisms underlying these relationships has proven difficult. The majority of risk SNPs, and nearby SNPs in linkag...

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Detalles Bibliográficos
Autores principales: Pierce, Steven, Coetzee, Gerhard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391096/
https://www.ncbi.nlm.nih.gov/pubmed/28407015
http://dx.doi.org/10.1371/journal.pone.0175882