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Association of Lyn kinase with membrane rafts determines its negative influence on LPS-induced signaling

Lipopolysaccharide (LPS) is the component of Gram-negative bacteria that activates Toll-like receptor 4 (TLR4) to trigger proinflammatory responses. We examined the involvement of Lyn tyrosine kinase in TLR4 signaling of macrophages, distinguishing its catalytic activity and intermolecular interacti...

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Detalles Bibliográficos
Autores principales:	Borzęcka-Solarz, Kinga, Dembińska, Justyna, Hromada-Judycka, Aneta, Traczyk, Gabriela, Ciesielska, Anna, Ziemlińska, Ewelina, Świątkowska, Anna, Kwiatkowska, Katarzyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391190/ https://www.ncbi.nlm.nih.gov/pubmed/28228554 http://dx.doi.org/10.1091/mbc.E16-09-0632

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