Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

Recent research has proposed that GIT2 (G protein-coupled receptor kinase interacting protein 2) acts as an integrator of the aging process through regulation of ‘neurometabolic’ integrity. One of the commonly accepted hallmarks of the aging process is thymic involution. At a relatively young age, 1...

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Detalles Bibliográficos
Autores principales: Siddiqui, Sana, Lustig, Ana, Carter, Arnell, Sankar, Mathavi, Daimon, Caitlin M., Premont, Richard T., Etienne, Harmonie, van Gastel, Jaana, Azmi, Abdelkrim, Janssens, Jonathan, Becker, Kevin G., Zhang, Yongqing, Wood, William, Lehrmann, Elin, Martin, James G., Martin, Bronwen, Taub, Dennis D., Maudsley, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391227/
https://www.ncbi.nlm.nih.gov/pubmed/28260693
http://dx.doi.org/10.18632/aging.101185

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