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Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age
Epigenetic regulation of various genomic functions, including gene expression, provide mechanisms whereby an organism can dynamically respond to changes in its environment and modify gene expression accordingly. One epigenetic mechanism implicated in human aging and age-related disorders is DNA meth...
Autores principales: | Benton, Miles C., Sutherland, Heidi G., Macartney-Coxson, Donia, Haupt, Larisa M., Lea, Rodney A., Griffiths, Lyn R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391229/ https://www.ncbi.nlm.nih.gov/pubmed/28255110 http://dx.doi.org/10.18632/aging.101187 |
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