Age-associated chromatin relaxation is enhanced in Huntington's disease mice

Expansion of polyglutamine stretch in the huntingtin (HTT) protein is a major cause of Huntington's disease (HD). The polyglutamine part in HTT interacts with various proteins implicated in epigenetic regulation of genes, suggesting that mutant HTT may disturb the integrity of the epigenetic sy...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Myungsun, Min, Byungkuk, Jeon, Kyuheum, Cho, Sunwha, Park, Jung Sun, Kim, Jisun, Jeon, Jeha, Song, Jinhoi, Kim, Seokho, Jeong, Sangkyun, Seo, Hyemyung, Kang, Yong-Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391233/
https://www.ncbi.nlm.nih.gov/pubmed/28288000
http://dx.doi.org/10.18632/aging.101193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391233/
https://www.ncbi.nlm.nih.gov/pubmed/28288000
http://dx.doi.org/10.18632/aging.101193

Ejemplares similares