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A new genome-mining tool redefines the lasso peptide biosynthetic landscape

Ribosomally synthesized and post-translationally modified peptide (RiPP) natural products are attractive for genome-driven discovery and re-engineering, but limitations in bioinformatic methods and exponentially increasing genomic data make large-scale mining difficult. We report RODEO (Rapid ORF De...

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Detalles Bibliográficos
Autores principales:	Tietz, Jonathan I., Schwalen, Christopher J., Patel, Parth S., Maxson, Tucker, Blair, Patricia M., Tai, Hua-Chia, Zakai, Uzma I., Mitchell, Douglas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391289/ https://www.ncbi.nlm.nih.gov/pubmed/28244986 http://dx.doi.org/10.1038/nchembio.2319

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