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Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study

If invasive ventilation can be avoided by performing noninvasive mechanical ventilation (NIV) in patients with acute respiratory failure (ARF), the disease can be effectively managed. It is important to clarify the characteristics of patients with neuromuscular diseases in whom initial NIV is likely...

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Autores principales: Kataoka, Hiroshi, Nanaura, Hitoki, Kinugawa, Kaoru, Uchihara, Yuto, Ohara, Hiroya, Eura, Nobuyuki, Syobatake, Ryogo, Sawa, Nobuhiro, Takao, Kiriyama, Sugie, Kazuma, Ueno, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391512/
https://www.ncbi.nlm.nih.gov/pubmed/28461884
http://dx.doi.org/10.4081/ni.2017.6904
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author Kataoka, Hiroshi
Nanaura, Hitoki
Kinugawa, Kaoru
Uchihara, Yuto
Ohara, Hiroya
Eura, Nobuyuki
Syobatake, Ryogo
Sawa, Nobuhiro
Takao, Kiriyama
Sugie, Kazuma
Ueno, Satoshi
author_facet Kataoka, Hiroshi
Nanaura, Hitoki
Kinugawa, Kaoru
Uchihara, Yuto
Ohara, Hiroya
Eura, Nobuyuki
Syobatake, Ryogo
Sawa, Nobuhiro
Takao, Kiriyama
Sugie, Kazuma
Ueno, Satoshi
author_sort Kataoka, Hiroshi
collection PubMed
description If invasive ventilation can be avoided by performing noninvasive mechanical ventilation (NIV) in patients with acute respiratory failure (ARF), the disease can be effectively managed. It is important to clarify the characteristics of patients with neuromuscular diseases in whom initial NIV is likely to be unsuccessful. We studied 27 patients in stable neuromuscular condition who initially received NIV to manage fatal ARF to identify differences in factors immediately before the onset of ARF among patients who receive continuous NIV support, patients who are switched from NIV to invasive ventilation, and patients in whom NIV is discontinued. Endpoints were evaluated 24 and 72 hours after the initiation of NIV. After 24 hours, all but 1 patient with amyotrophic lateral sclerosis (ALS) received continuous NIV support. 72 hours later, 5 patients were switched from NIV to invasive ventilation, and 5 patients continued to receive NIV support. 72 hours after the initiation of NIV, the proportion of patients with a diagnosis of ALS differed significantly among the three groups (P=0.039). NIV may be attempted to manage acute fatal respiratory failure associated with neuromuscular diseases, but clinicians should carefully manage the clinical course in patients with ALS.
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spelling pubmed-53915122017-05-01 Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study Kataoka, Hiroshi Nanaura, Hitoki Kinugawa, Kaoru Uchihara, Yuto Ohara, Hiroya Eura, Nobuyuki Syobatake, Ryogo Sawa, Nobuhiro Takao, Kiriyama Sugie, Kazuma Ueno, Satoshi Neurol Int Article If invasive ventilation can be avoided by performing noninvasive mechanical ventilation (NIV) in patients with acute respiratory failure (ARF), the disease can be effectively managed. It is important to clarify the characteristics of patients with neuromuscular diseases in whom initial NIV is likely to be unsuccessful. We studied 27 patients in stable neuromuscular condition who initially received NIV to manage fatal ARF to identify differences in factors immediately before the onset of ARF among patients who receive continuous NIV support, patients who are switched from NIV to invasive ventilation, and patients in whom NIV is discontinued. Endpoints were evaluated 24 and 72 hours after the initiation of NIV. After 24 hours, all but 1 patient with amyotrophic lateral sclerosis (ALS) received continuous NIV support. 72 hours later, 5 patients were switched from NIV to invasive ventilation, and 5 patients continued to receive NIV support. 72 hours after the initiation of NIV, the proportion of patients with a diagnosis of ALS differed significantly among the three groups (P=0.039). NIV may be attempted to manage acute fatal respiratory failure associated with neuromuscular diseases, but clinicians should carefully manage the clinical course in patients with ALS. PAGEPress Publications, Pavia, Italy 2017-03-28 /pmc/articles/PMC5391512/ /pubmed/28461884 http://dx.doi.org/10.4081/ni.2017.6904 Text en ©Copyright H. Kataoka et al., 2017 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Kataoka, Hiroshi
Nanaura, Hitoki
Kinugawa, Kaoru
Uchihara, Yuto
Ohara, Hiroya
Eura, Nobuyuki
Syobatake, Ryogo
Sawa, Nobuhiro
Takao, Kiriyama
Sugie, Kazuma
Ueno, Satoshi
Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study
title Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study
title_full Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study
title_fullStr Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study
title_full_unstemmed Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study
title_short Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study
title_sort risk of unsuccessful noninvasive ventilation for acute respiratory failure in heterogeneous neuromuscular diseases: a retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391512/
https://www.ncbi.nlm.nih.gov/pubmed/28461884
http://dx.doi.org/10.4081/ni.2017.6904
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