Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51

Artesunate, a semi-synthetic derivative of arteminisin originally developed for the treatment of malaria, has recently been shown to possess antitumor properties. One of the cytotoxic effects of artesunate on cancer cells is mediated by induction of oxidative stress and DNA double-strand breaks (DSB...

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Detalles Bibliográficos
Autores principales: Wang, Bingliang, Hou, Dong, Liu, Qiao, Wu, Tingting, Guo, Haiyang, Zhang, Xiyu, Zou, Yongxin, Liu, Zhaojian, Liu, Jinsong, Wei, Jianjun, Gong, Yaoqin, Shao, Changshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391513/
https://www.ncbi.nlm.nih.gov/pubmed/26176175
http://dx.doi.org/10.1080/15384047.2015.1071738

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