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Advances of CD19-directed chimeric antigen receptor-modified T cells in refractory/relapsed acute lymphoblastic leukemia

Refractory/relapsed B-cell acute lymphoblastic leukemia remains to be a significant cause of cancer-associated morbidity and mortality for children and adults. Developing novel and effective molecular-targeted approaches is thus a major priority. Chimeric antigen receptor-modified T cell (CAR-T) the...

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Detalles Bibliográficos
Autores principales: Wei, Guoqing, Ding, Lijuan, Wang, Jiasheng, Hu, Yongxian, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391552/
https://www.ncbi.nlm.nih.gov/pubmed/28413717
http://dx.doi.org/10.1186/s40164-017-0070-9