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Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry

Marburg virus (MARV) is a lipid-enveloped virus from the Filoviridae family containing a negative sense RNA genome. One of the seven MARV genes encodes the matrix protein VP40, which forms a matrix layer beneath the plasma membrane inner leaflet to facilitate budding from the host cell. MARV VP40 (m...

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Detalles Bibliográficos
Autores principales:	Wijesinghe, Kaveesha J., Urata, Sarah, Bhattarai, Nisha, Kooijman, Edgar E., Gerstman, Bernard S., Chapagain, Prem P., Li, Sheng, Stahelin, Robert V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Lipids
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391744/ https://www.ncbi.nlm.nih.gov/pubmed/28167534 http://dx.doi.org/10.1074/jbc.M116.758300

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